Example sentences for: ihh

How can you use “ihh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For example, Collagen II expression (splice form A) is increased, as is Ihh mRNA, and Bmp-4 and p107 expression are decreased.

  • Bmp-2 signaling has a positive effect on chondrocyte proliferation [ 29 ] , and can induce Indian hedgehog (Ihh) expression in responsive cells [ 30 ] . We find Ihh mRNA elevated in Hoxc-8 transgenic chondrocytes (see Figure 8).

  • Ihh can induce Bmp expression in proliferating cells, further increasing positive effects on chondrocyte proliferation [ 31 ] . At the same time, Ihh decreases the rate of progression to hypertrophy [ 32 33 ] , again consistent with an accumulation of proliferating cells in our transgenic animals.

  • This is most likely due to Ihh signaling in these tissues [ 26 ] . Both Shh and Ihh signaling were dependent on Smo, however, because Ptc1 expression could not be detected in Smo -/-embryos (Figure 3o).

  • Whether the elevated Ihh mRNA levels originate from increased expression in cells that make Ihh normally (prehypertrophic and hypertrophic chondrocytes) or from ectopic activation by the Hox transcription factors in proliferating cells, remains to be investigated.

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