Example sentences for: ihc
How can you use “ihc” in a sentence? Here are some example sentences to help you improve your vocabulary:
MCM2 and Ki-67 expression in bronchial biopsy specimens from patients at risk for lung cancer or with suspected lung cancer were studied by immunohistochemistry (IHC).
Clinically, TYRP-1 is thought to be important as a melanoma antigen that is highly antigenic to cytotoxic T cells, providing a potential target for melanoma vaccine development [ 16 ] . TYRP-1 appears to be less expressed in advanced primary lesions and metastases of human cutaneous melanoma and uveal melanoma [ 32 ] . Primary melanoma samples express TYRP-1 transcripts at higher levels than melanoma metastases [ 33 ] , and IHC analysis of malignant melanocytic lesions has shown that the invasive cells of primary melanomas are TYRP-1-negative [ 34 ] .
In 41 specimens, the morphology was comparable between the original slide and slide 5. These 41 specimens were used for IHC analysis and included morphologically normal bronchial mucosa, metaplasia, dysplasia, and CIS (see Table 1for the numbers of specimens with normal and abnormal morphology).
We used a combination of immunohistochemistry (IHC), LCM and real-time, quantitative PCR (qPCR) analysis of material obtained from a panel of primary breast infiltrating ductal carcinomas and nodal metastases, and compared the target gene expression levels with those found in nonmalignant diseased tissue and in samples of normal breast tissue.
Our LCM-mediated transcript detection acts as an important confirmation of breast tumor cell OPN synthesis because IHC analysis does not rule out the possibility that secreted proteins such as OPN and TSP-1 are sequestered by the tumor cells from the local environment.
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