Example sentences for: iggsd

How can you use “iggsd” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The present observations demonstrate that the frequencies of HLA-A and -B phenotypes and haplotypes were not significantly different in CVID and IgGSD index patients, with few exceptions.

  • This is consistent with evidence for the occurrence on Ch6p of multiple distinct susceptibility genes for patterns of immunoglobulin deficiency, some recessive and others dominant [ 20 ] . For example, at least two putative alleles associated with heritable IgA deficiency occur on Ch6p, and each is associated with a different major histocompatibility (MHC) region haplotype [ 22 23 ] , whereas a putative susceptibility locus on chromosome 18 is not a major contributor to selective IgA deficiency [ 24 ] . Allele(s) on chromosomes other than Ch6p may also influence the phenotypic expression of CVID and IgGSD in adults.

  • CVID and IgGSD Index Cases

  • This indicates that a susceptibility locus (loci) for CVID and IgGSD occurs on multiple haplotypes defined by HLA-A and -B typing.

  • Alternatively, the variable immunoglobulin deficiency phenotypes presently classified as CVID and IgGSD are best explained by the co-inheritance of multiple alleles, each of which has an independent effect on the immunoglobulin deficiency phenotype.


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