Words similar to ifn-γ
Example sentences for: ifn-γ
How can you use “ifn-γ” in a sentence? Here are some example sentences to help you improve your vocabulary:
The question resolves into two parts: are TNF-α and IFN-γ levels increased in the HIV +and aged states, and do the CD8 +T cells show increased production of these cytokines.
Collectively, these findings are consistent with the observations that Th1 cells are associated with erosive disease [ 39 50 51 ] , that IFN-γ does not have antiresorptive activity [ 52 53 54 ] , and that IL-4 inhibits bone resorption [ 55 56 57 ] .
The data suggest that IL-10 is important for controlling IFN-γ and/or other cytokines involved in the process of CD11b +cell expansion.
Interestingly, both IFN-γ and TNF-α are prominent in the pathogenesis of autoimmune diseases in general; the former by activation of local auto antigen presentation to appropriate T cells, and the latter by mediation of inflammatory tissue damage [ 68 ] . Apparently TNF-α plays a central role in the chronic release of highly arthritogenic II-1 [ 69 ] , and thus serves as a major factor in the pathogenesis of rheumatoid arthritis (RA) [ 69 ] . Recent studies show that treatment with anti-TNF-α gives significant clinical improvement in RA [ 70 ] . Thus our findings in aged individuals of a prominent CD8 +CD28 -T cell subset with enhanced ability to produce TNF-α, may assume clinical relevance.
Freshly isolated lung lymphocytes that were not otherwise manipulated secreted high levels of IFN-γ, MIG, and IP-10, with significantly greater secretion of both cytokines from lymphocytes of participants with emphysema (Figure 3A–3C).
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