Words similar to ifn
Example sentences for: ifn
How can you use “ifn” in a sentence? Here are some example sentences to help you improve your vocabulary:
Anti-TNF-α = anti-tumor necrosis factor alpha; ELISA = enzyme-linked immunosorbent assay; hTNF-α = human tumor necrosis factor alpha; IFN = interferon; IL = interleukin; mAb = monoclonal antibody; mRNA = messenger ribonucleic acid; MTX = methotrexate; PCR = polymerase chain reaction; RA = rheumatoid arthritis; TNF-α = tumor necrosis factor alpha.
COX = cyclooxygenase; HF = human fibroblasts; NL = normal lungs; IPF = idiopathic pulmonary fibrosis; IFN = interferon; IL = interleukin; PG = prostaglandin; TX = thromboxane; PGI 2 = prostacyclin.
(iii) Lack of interferon response: We provide direct experimental evidence that the 21-nt dsRNA does not trigger an IFN response, which is an advantage because an IFN response would have caused a general and non-specific inhibition of all cap-dependent translation [ 5 ] . (iv) Regulation any time: Although we have not tested this specifically, one can, in principle, transfect the virus-infected cell with dsRNA at any time point during infection.
The largest group is composed of genes associated with the term 'interferon' (also 'IFN' and 'IFN-alpha', color coded green, Figure 2); indeed, STATs are factors specifically required for interferon signaling.
Interestingly, the IFN response requires long dsRNA [ 5 6 ] , and it has been conjectured that the improved specificity of the 21-nucleotide long dsRNA in cultured mammalian cells is probably due to their inability to activate the IFN response [ 2 ] . We provide several lines of direct and indirect evidence that the dsRNAs described here did not activate a general IFN response.
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