Words similar to ictal

Example sentences for: ictal

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reported that under epileptogenic condition (free Mg 2+in ACSF), γ band oscillations arise from GABAergic depolarizations and that this activity may lead to the generation of ictal discharges [ 18 ] . It has been reported that prolonged periods of γ oscillations are associated with temporal lobe seizures in in vivo rats [ 41 ] . Furthermore, human EEG studies with subdural recording electodes showed that a γ band oscillation could be recorded at the start of typical seizure activity [ 42 ] . In this respect, the hyperthermic γ oscillations may also play a critical role in generation of neuronal epileptiform activity.
If γ oscillations do prove to be important in clinical febrile seizures, then future work might profitably examine the therapeutic potential of mild disinhibition to disrupt inhibitory GABA-mediated synchrony at the start of ictal activity.
The specific GABA A receptor antagonist, bicuculline, blocks the γ oscillations [ 14 16 ] , an action that can be modeled by simulated neuronal networks [ 17 ] . The γ band oscillations appear to play an important role in generation of ictal epileptiform activity in hippocampal slices [ 18 ] . This study explores the role of γ oscillations in epileptiform activity in the hyperthermic rat hippocampal slice.