Words similar to icam-
Example sentences for: icam-
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There is now compelling evidence demonstrating that CD9, a tetraspan membrane protein, is present on the oolemma and essential for sperm-egg fusion, possibly by organizing functional multimolecular complexes in the egg [ 7 ] . Glycosyl-phophatidyniositol (GPI)-anchored proteins have also been described on the oolemma and implicated in sperm-egg fusion; removal of GPI-anchored protein from the egg plasma membrane results in greatly reduced fertilization rates without affecting sperm-zona pellucida binding [ 8 ] . Other egg surface molecules are the adhesion molecules NCAM, VCAM-1, ICAM-1 and ECAD [ 9 ] , and the selectins [ 10 ] . Additionally, the IgG receptor [ 11 ] , complement receptors C1q [ 12 ] , CD35 and CD11b, [ 13 ] and the Fc gamma receptors [ 14 ] exhibit oolemmal expression in a variety of mammalian species.
Sepsis is associated with a rapid release of CXC chemokines by alveolar macrophages, as well as up regulation of lung vascular intercellular adhesion molecule-1 (ICAM-1) expression [ 26 ] and these may contribute to the initial increase in adherent vascular neutrophils in the lung.
It has also been reported that inhibition of endothelial nitric oxide synthases (using the non-selective NOS inhibitor L-NAME), induces endothelial adhesion molecules (ICAM-1 and VCAM-1) in HUVEC [ 24, 25].
Monoclonal antibodies VCAM, STRO-1, ICAM-1(CD54), CD105, CD29, and MF20 were from Developmental Studies Hybridoma Bank (University of Iowa, Iowa City, Iowa, United States); CD73, CD44, and ALCAM(CD166) were from BD Biosciences Pharmingen (San Diego, California, United States).
However, since MAdCAM-1 is induced by Th1 cytokines, like TNF-α and IL-1b, it is likely that its induction is mechanistically similar to that of adhesion molecules like ICAM-1 and VCAM-1.
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