Example sentences for: hyperinsulinemia

How can you use “hyperinsulinemia” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The WHR, a measure of central adiposity, is gaining increased use as a measure of etiologically significant obesity and is thought to be more closely related to pathology, especially coronary heart disease, diabetes mellitus and stroke [ 7 ] . The metabolic changes that accompany obesity include peripheral hyperinsulinemia, hyperglycemia and glucose intolerance, hypertriglyceridemia, decreased serum low-density lipoprotein, increased serum very low-density lipoprotein, increased serum leptin, dyslipidemia, increased serum cortisol clearance, increased serum C-peptide level, downregulation of insulin receptors and an exaggerated insulin response to an oral glucose load [ 12 13 14 15 ] . These changes, especially when they occur in early adulthood, may be of fundamental importance in the development of breast cancer [ 9 16 ] .

  • Although a state of endogenous hyperinsulinemia occurs, the degree of tissue resistance causes a total decrease in “effective” endogenous insulin.

  • It is the body's ability to maintain glucose utilization and suppress endogenous glucose production in the setting of this compensatory hyperinsulinemia that separates metabolic syndrome from diabetes.

  • For example, diabetes, visceral obesity, hypertension, and hyperinsulinemia commonly aggregate together in large populations, and are considered a “metabolic syndrome” that has been linked to SDB [16] and to inflammatory disorders [17].

  • This syndrome is characterized not only by the criteria given in Table 1, but also by a state of compensatory hyperinsulinemia [14].


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