Words similar to hyperalgesia

Example sentences for: hyperalgesia

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Although cytokines are traditionally associated with peripheral immune reactions as part of the innate response, evidence is accumulating that they may also be involved in normal brain function and may mediate pathological responses such as hyperalgesia [ 26 27 ] . In fact, the abundance of MIF in glia of the spinal cord is particularly interesting since glial cells have been suggested as involved in hyperalgesia through the release of cytokines and other substances [ 28 ] . Given the presence of MIF in the pelvic organs (bladder, prostate) and the central and peripheral nervous system tissues that innervate these organs, as well as the fact that bladder inflammation appears to upregulate MIF in these areas, it is possible that MIF represents a therapeutic target in reducing or preventing pelvic viscera inflammation.