Example sentences for: hybrid-fold-recognition

How can you use “hybrid-fold-recognition” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The hybrid-fold-recognition method, which combines sequence-profile analysis with alignment-based secondary-structure prediction [ 22] and the 3D-PSSM method [ 23] both suggested a likely α-amylase-like triosephosphate isomerase (TIM) barrel structure for this protein family.

  • Despite the relatively low sequence similarity to bacterial DHPS, all archaeal orthologs have the conserved catalytic residues identified in DHPS (Figure 2) and are confidently predicted, by the hybrid-fold-recognition method, to assume the same fold as DHPS from Pneumocystis carinii and Staphylococcus aureus whose crystal structures have been determined.


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