Words similar to htnf-α
Example sentences for: htnf-α
How can you use “htnf-α” in a sentence? Here are some example sentences to help you improve your vocabulary:
Mechanistically, the therapeutic effect of anti-TNF-α appears to be due to either neutralization of soluble hTNF-α or inhibition of hTNF-α production in the diseased joint.
Heterozygous Tg197 transgenic mice, obtained from Dr George Kollias (Hellenic Pasteur Institute, Athens, Greece) [ 7 ] , were identified by PCR analysis using primers to the 3'-modified hTNF-α gene.
Anti-TNF-α = anti-tumor necrosis factor alpha; ELISA = enzyme-linked immunosorbent assay; hTNF-α = human tumor necrosis factor alpha; IFN = interferon; IL = interleukin; mAb = monoclonal antibody; mRNA = messenger ribonucleic acid; MTX = methotrexate; PCR = polymerase chain reaction; RA = rheumatoid arthritis; TNF-α = tumor necrosis factor alpha.
The murine anti-TNF-α mAb used in this study binds with high affinity to hTNF-α and prevents binding to the TNF receptor [ 10 ] . Anti-TNF-α mAb was administered by intraperitoneal injection at 10 mg/kg weekly and the animals in the control group received weekly injections of saline.
These results demonstrate that blocking hTNF-α reverses joint inflammation and promotes joint healing in this model of polyarthritis.