Words similar to htnf-α
Example sentences for: htnf-α
How can you use “htnf-α” in a sentence? Here are some example sentences to help you improve your vocabulary:
First, circulating hTNF-α levels as detected by ELISA were more than halved as early as 3 weeks and the reduction was sustained for 16 weeks after treatment with anti-TNF-α mAb in comparison with saline-treated animals (Fig.
Progression of established polyarthritis in the Tg197 hTNF-α transgenic mouse can be reversed by treatment with anti-TNF-α mAb, as shown by significant improvement in clinical and histological scores.
Anti-TNF-α = anti-tumor necrosis factor alpha; ELISA = enzyme-linked immunosorbent assay; hTNF-α = human tumor necrosis factor alpha; IFN = interferon; IL = interleukin; mAb = monoclonal antibody; mRNA = messenger ribonucleic acid; MTX = methotrexate; PCR = polymerase chain reaction; RA = rheumatoid arthritis; TNF-α = tumor necrosis factor alpha.
Interestingly, local expression of murine TNF-α mRNA was not affected by treatment with anti-TNF-α antibodies, suggesting that hTNF-α plays a crucial role in the pathogenesis of arthritis in this model.
These results demonstrate that blocking hTNF-α reverses joint inflammation and promotes joint healing in this model of polyarthritis.