Example sentences for: htnf-α

How can you use “htnf-α” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mechanistically, the therapeutic effect of anti-TNF-α appears to be due to either neutralization of soluble hTNF-α or inhibition of hTNF-α production in the diseased joint.

  • Anti-TNF-α = anti-tumor necrosis factor alpha; ELISA = enzyme-linked immunosorbent assay; hTNF-α = human tumor necrosis factor alpha; IFN = interferon; IL = interleukin; mAb = monoclonal antibody; mRNA = messenger ribonucleic acid; MTX = methotrexate; PCR = polymerase chain reaction; RA = rheumatoid arthritis; TNF-α = tumor necrosis factor alpha.

  • First, circulating hTNF-α levels as detected by ELISA were more than halved as early as 3 weeks and the reduction was sustained for 16 weeks after treatment with anti-TNF-α mAb in comparison with saline-treated animals (Fig.

  • These results demonstrate that blocking hTNF-α reverses joint inflammation and promotes joint healing in this model of polyarthritis.

  • The murine anti-TNF-α mAb used in this study binds with high affinity to hTNF-α and prevents binding to the TNF receptor [ 10 ] . Anti-TNF-α mAb was administered by intraperitoneal injection at 10 mg/kg weekly and the animals in the control group received weekly injections of saline.


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