Words similar to houde

Example sentences for: houde

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Acute pain has been studied in single dose designs first proposed by Beecher and colleagues [ 1 2 ] and formalized by Houde and Wallenstein [ 3 ] . The problem with single trials is that while they can demonstrate statistical superiority of analgesic over placebo, variation because of random chance means that, if small, they provide a poor estimate of the size of the analgesic effect [ 4 ] . Combining results from clinically homogeneous trials in a meta-analysis gives an accurate estimate of the extent of the analgesic effect when sufficient numbers of patients have been randomized [ 4 5 ] .