Example sentences for: hormone-dependent

How can you use “hormone-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • NRs consist of three domains, the N-terminal domain (which contains a context-specific activation function AF-1), the central DNA binding domain (DBD) and the C-terminal ligand binding domain (LBD), which contains a hormone-dependent activation function, AF-2.

  • In conclusions, we report here that: 1) a constitutively active form of Stat3 stimulates transcriptional activity of SHRs in a hormone-dependent manner; 2) active Stat3 can act synergistically with other c oactivators to stimulate SHRs transcriptional activity; 3) Stat3 did not affect specificity of AR to other steroid hormones different than androgen, or binding of AR to other HREs; 4) Stat3 increases the sensitivity of AR to androgen.

  • In addition, it has been demonstrated [ 20] that hormone-dependent tumors such as breast and ovarian cancers have a decreased ability to undergo apoptosis.

  • cardiovascular disease and osteoporosis) and hormone-dependent cancers (i.e.

  • The hormone-dependent component of the ERβ /N-CoR interaction maps to the extreme C-terminus of N-CoR, which has not been previously implicated in NR interactions, and requires a sequence that resembles an ERβ-specific NR box (PLTIRMLS, β-box).


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