Example sentences for: hormone-dependent

How can you use “hormone-dependent” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The hormone-dependent component of the ERβ /N-CoR interaction maps to the extreme C-terminus of N-CoR, which has not been previously implicated in NR interactions, and requires a sequence that resembles an ERβ-specific NR box (PLTIRMLS, β-box).

  • Mutation of N-CoR to obtain a β-box sequence that more closely resembled a conventional LXXLL motif (T2402L) led to enhanced hormone-dependent interactions with ERβ and permitted novel hormone-dependent interactions with ERα (Fig.

  • In addition it has been demonstrated [ 20] that hormone-dependent tumors such as breast and ovarian cancers have a decreased ability to undergo apoptosis.

  • The finding that estrogens suppress N-CoR binding to ERα [ 39 ] , but promote N-CoR binding to ERβ represents the first demonstration of a corepressor that shows completely distinct modes of hormone-dependent interaction with the ER isoforms.

  • cardiovascular disease and osteoporosis) and hormone-dependent cancers (i.e.


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