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Example sentences for: holliday
How can you use “holliday” in a sentence? Here are some example sentences to help you improve your vocabulary:
Mutations in genes involved in processing Holliday structures - recG, ruvAB and ruvC - did not lead to their accumulation.
Game and his colleagues have developed a sensitive means of detecting chromosomal ds breakage using a circular chromosome [ 3 ] . Under most conditions of pulsed-field gel electrophoresis, a circular yeast chromosome and circular bacterial chromosomes will not enter the gel, very likely because they are trapped by the branches of the network of agarose [ 3 13 14 ] . One double-strand break transforms this circular form into a linear form, which can now move slowly in the gel [ 3 ] . We used this procedure to detect double-strand breakage of a circular bacterial chromosome occurring spontaneously or after loss of a restriction-modification gene complex [ 15 16 ] . We found increased chromosome breakage in recBC -null and recC1002 mutants of E. coli under both conditions [ 1 ] . Michel and her colleagues used pulsed-field gel electrophoresis to detect degraded chromosomal DNAs arising spontaneously in recBC mutants and arising during replication fork arrest [ 2 ] . RuvABC proteins, which catalyze migration and cleavage of Holliday junctions, are responsible for the occurrence of the degraded DNAs following replication fork arrests [ 17 ] .
Holliday junctions, for example, are intermediates that occur during genetic recombination.
I commented then that Mata Hari and Judge Roy Bean were both in but that Doc Holliday was missing: Holliday is still on vacation and now the old Bean has joined him.
To model Holliday junctions, a stable four-arm junction has been constructed in which, by design, no two strands are fully complementary to each other (Kallenback et al.
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