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Example sentences for: hlod

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Several biostatisticians have suggested that general models provide power to distinguish linkage signals independent of the true underlying disease mode of inheritance, provided both dominant and recessive models are used [ 38 39 40 ] . As expected, the highest two-point and multipoint LOD scores were obtained in the HLA region, with a two-point HLOD of 3.1 and a multipoint HLOD of 5.0.
The highest 2-point HLOD scores obtained with either model are shown in Table 3. The multipoint HLODs were obtained using the same model as the 2-point HLOD shown.
Under the dominant model, the two-point HLOD was 3.1 (α = 1.0) at D6S426 (position 60.
Of the 13 candidate gene regions investigated, none of the regions had even nominal evidence for linkage (HLOD > 1.3) or an NPL score with p < 0.05.
4 cM), the multi-point HLOD was 5.02 (α = 0.66) (position 54.