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Example sentences for: hivan

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[ 21 ] Therefore, use of antiretroviral therapy would be expected in patients with HIVAN in the absence of definite contraindications, even disregarding the previously cited reports of a possible beneficial effect of HAART on the course of HIVAN itself.
Recent anecdotal reports of remission of HIVAN with use of HAART are encouraging.
In stratified analysis limited to patients with HIVAN, ACE use was not significantly associated with mortality (p = 0.48, AHR = 1.88, 95% CI, 0.33-10.
Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.
Plots of survival by ACE use are shown for HIVAN patients (Figure 2) and for the entire study cohort (Figure 3).