Words similar to hiv-
Example sentences for: hiv-
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The interaction between HIV-1 IIIB, a representative of X4 viruses, and HIV-1 BaL, a representative of R5 viruses, with the micronized form of CAP has the following consequences: 1) elicitation of "dead-end" gp41 six-helix bundles expected to render the virus incompetent to fuse with target cells; 2) loss of virus integrity and stripping off of the envelope glycoproteins; and 3) inactivation of virus infectivity.
These HIV-1-specific CD4+ T cell responses also tended to rise with reinitiation of therapy, and some of them were very robust, with stimulation indices over 50 detected in several individuals (Figure 3E).
In order to correlate the properties of CAP in soluble and micronized forms, it was necessary to establish whether or not micronized CAP would bind HIV-1 virus particles and HIV-1 envelope glycoproteins, and induce the formation of gp41 six-helix bundles, a marker of irreversible virus inactivation, as did soluble CAP [ 37 ] . First it was established that HIV-1 gp120 bound to micronized CAP (provided in the form of micronized CAP particles or of a commercial product, "Aquateric", containing about 66% of CAP and used for enteric coating of tablets and capsules in the pharmaceutical industry [ 54 ] ); (Fig.
The dissociation constants (K d ) of the E-TP binary complexes of the wild type HIV-1 RT and its mutant derivatives were determined as described by Tong et al.
Inhibition of HIV-1 infection