Example sentences for: histocompatibility

How can you use “histocompatibility” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For instance, HIV-1 infection is able to down-regulate major histocompatibility complex type I (MHC-I) by various different viral proteins, including Tat which represses the transcription of MHC-I, Vpu which retains nascent MHC-I chains in the endoplasmic reticulum, and Nef which can mediate selective internalization of MHC-I molecules from the plasma membrane.

  • MDC, monocyte-derived cells; b, basal layer; pb, parabasal layers; im, intermediate layers; s, superficial layers; Ip, lamina propria; MHC, major histocompatibility complex; Ig, immunoglobulin; DC, dendritic cells; TCU, tissue control unit; PBS, phosphate-buffered saline; FITC, fluorescein-isothiocyanate; IHC, immunohistochemistry.

  • TCR, T cell receptor; MHC, major histocompatibility complex; H-2, murine MHC locus; Tag, SV40 T antigen; RIP, rat insulin promoter; RAG, recombinase activating gene.

  • The role of genetics in modulating the immune response to infectious diseases is a topic of longstanding interest among epidemiologists, clinicians, population geneticists, and immunologists [ 1 2 ] . Zinkernagel and Doherty's Nobel Prize-winning discovery that cellular immunity to viral infections was "restricted" by the highly variable proteins of the Major Histocompatibility Complex (MHC) brought the field of immunogenetics into sharper focus [ 3 ] . Their demonstration that T lymphocytes recognize virus antigens displayed on a host cell "in the context of" MHC proteins immediately suggested the idea that genetic differences at the loci encoding the MHC might modulate the intensity and effectiveness of host response to infection.

  • In our example, giving occurrence values for terms such as 'apoptosis', 'endothelial', 'interferon', 'inflammatory' 'chemoattractant' or 'histocompatibility' provides a 'naive' reader with insight into the function attributed in the literature to each of the listed genes.


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