Example sentences for: histocompatibility

How can you use “histocompatibility” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 2002), or genes encoding reconnaissance molecules known as the major histocompatibility complex (MHC), which control the action of T-cells (Hughes and Nei 1988; Yeager and Hughes 1999) (Box 1).

  • Such regions include the class III major histocompatibility complex and histone gene clusters on chromosome 6, the human alpha-globin gene cluster located on chromosome 16, and others.

  • This is consistent with evidence for the occurrence on Ch6p of multiple distinct susceptibility genes for patterns of immunoglobulin deficiency, some recessive and others dominant [ 20 ] . For example, at least two putative alleles associated with heritable IgA deficiency occur on Ch6p, and each is associated with a different major histocompatibility (MHC) region haplotype [ 22 23 ] , whereas a putative susceptibility locus on chromosome 18 is not a major contributor to selective IgA deficiency [ 24 ] . Allele(s) on chromosomes other than Ch6p may also influence the phenotypic expression of CVID and IgGSD in adults.

  • AS = ankylosing spondylitis; B27 = histocompatibility antigen B27; CREST = calcinosis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, telangiectasia; E 2 = estradiol-17β JRA = juvenile rheumatoid arthritis; RA = rheumatoid arthritis; RAD = rheumatic/autoimmune disease; SLE = systemic lupus erythematosus.

  • For instance, HIV-1 infection is able to down-regulate major histocompatibility complex type I (MHC-I) by various different viral proteins, including Tat which represses the transcription of MHC-I, Vpu which retains nascent MHC-I chains in the endoplasmic reticulum, and Nef which can mediate selective internalization of MHC-I molecules from the plasma membrane.


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