Words similar to histidine
Example sentences for: histidine
How can you use “histidine” in a sentence? Here are some example sentences to help you improve your vocabulary:
The human FHIT gene, located at the chromosome 3 fragile site FRA3B, is inactivated early in the development of many tumors [ 1 ] . Murine Fhit is also located at a fragile site [ 2 3 ] and mice heterozygous for disruption of Fhit , given low intragastric doses of the mutagen N-nitrosomethylbenzylamine, develop stomach and sebaceous tumors [ 4 ] that can be prevented by viral Fhit expression [ 5 ] . Fhit, a dimer of 147 amino acid subunits, is a member of the histidine triad (HIT) superfamily of nucleotide hydrolases and transferases [ 6 7 ] . Members of the Hint branch of the HIT superfamily are found in all forms of life [ 8 ] . The S. cerevisiae Hint homolog, Hnt1, and rabbit Hint possess adenosine monophosphoramidase activity that functions in yeast to positively regulate function of Kin28, Ccl1 and Tfb3, which constitute the kinase component of general transcription factor TFIIH [ 9 ] . A new Hint related protein, Aprataxin, is mutated in individuals with ataxia with oculomotor apraxia [ 10 11 ] and has a yeast homolog termed Hnt3 [ 9 ] . Members of the Fhit branch of the HIT superfamily have been found in fungi [ 12 13 ] , animals [ 2 14 15 ] and plants [ 7 ] and hydrolyze diadenosine tetraphosphate, diadenosine triphosphate and other 5'-5"'-dinucleoside polyphosphates.
The configuration, comprising a catalytic cysteine at the amino terminus of a helix packed against a core three-stranded β-sheet, with the second and third strands bearing the catalytic histidine and its orienting polar partner, is seen in the transglutaminases and a related class of amino-group acetyltransferases, papain-like proteases, adenoviral proteases and ubiquitin carboxy-terminal hydrolases [ 32, 38] (Figure 2).
The NlpC/P60 domain is predicted to adopt a papain-like fold, in which the catalytic cysteine is at the amino terminus of a helix, which is packed against a five-stranded β-barrel with the histidine and the polar residue.
These include enzymatic domains such as nucleotide cyclases, histidine and serine/threonine kinases, cNMP phosphodiesterases, receiver domains and several different kinds of ATPases [ 3 4 ] . Non-catalytic domains, like DNA- or RNA-binding modules (eg.
This linker encoded in frame the amino acids MSHHHHHHSM, with the last residue corresponding to the first methionine encoded in rec12 +exon 1. Trimolecular ligation was used to create pREP2- rec12 +, pREP42- rec12 +, and pREP82- rec12 +clones encoding Rec12 protein with 6X histidine tags.
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