Words similar to hippocampal
Example sentences for: hippocampal
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In in vitro studies, carbenoxolone abolished the generation of full or partial ectopic spike generation, by 4-AP, in the CA 3 region of rat hippocampal slices [ 6 ] . Also carbenoxolone depresses spontaneous epileptiform activity in the CA 1 region of rat hippocampal slices [ 7 ] . Carbenoxolone appears to cross the blood brain barrier about one hour after an intraperitoneal injection in rats as there was the inhibition of 11-β-hydroxysteroid dehydrogenase in multiple brain regions [ 1 ] . It and/or its congener glycyrrehetinic acid may also enter the eyes of humans.
In examining hippocampal CALB levels between Phyto-600 vs.
POMC is cleaved post-translationally producing bioactive peptides (adrenocorticotrophin, β-endorphin and α-, β- and γ-melanocyte stimulating hormones) that interact with neurons expressing melanocortin receptors, leading to appetite suppression [ 91 ] . Feeding high fat diets is known to increase Pomc expression [ 92 ] . Herein, FUNG feeding resulted in a 6.0* fold increase in hippocampal Pomc, whereas FISH and the combination diet had smaller, non-statistically significant effects (6.
Fish oil feeding is well established to increase n3 LC-PUFA in hepatic PL as well as whole brain PL [ 18 ] ; whereas deficiency of n3 LC-PUFA can decrease 22:6n-3 in hippocampal PL [ 25 ] . DHA present in the brain can be formed from precursors in the liver or astrocytes, and intact DHA passes the blood brain barrier via selective transport mechanisms [ 26 ] . These data confirm that diets did result in actual increases in the brain of the appropriate FAs and set the stage for interpreting transcriptional responses observed in each organ.
The γ frequency oscillations (30-100 Hz) are characteristic of responses to sensory input measured by cortical EEG [ 9 ] . In the hippocampal slice preparation, γ oscillations can be evoked by brief, high frequency tetanic stimuli to region CA1 [ 10 11 12 13 ] . The extracellular field potential response during these oscillations takes the form of a train of population spikes in stratum pyramidal at γ and β (15-30 Hz) frequencies [ 14 ] . Intracellular recordings during γ oscillations induced by tetanic stimulation reveal a slow membrane depolarization in conjunction with GABA A receptor-mediated inhibitory postsynaptic potentials [ 11 15 ] . This synaptic inhibition-based γ activity entrains action potential generation in pyramidal neurons, leading to the population spikes at γ band frequencies.