Example sentences for: hinge

How can you use “hinge” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This was further supported by the demonstration that trypsin cleaved PP5 in the "hinge" sequence connecting the TPR region and catalytic domain, and that such cleavage produced a highly active enzyme which was refractory to further activation by fatty acids [ 18 20 21 ] . To test whether this is also true of PfPP5, we digested recombinant PfPP5 with trypsin, which resulted in the production of a trypsin-resistant fragment that was very similar in size to ΔTPR-PfPP5 (Fig.

  • In this study, By producing wtPAI-1 and several single site mutations in the distal hinge of PAI-1 in a baculovirus expression system, we were able to find out the role of the distal hinge in conformational transition of PAI-1 and to elucidate the role of Glu351 in PAI-1 for serine protease specificities.

  • Several lines of argument hinge on it.

  • The RCL contains the residues Ser331 to Arg356 (P16-P10'), and within it there is a peptide loop (Glu 351 to Pro 357, P5'-P11'), which is defined as the distal hinge (Table 1).

  • As such, an organization's success in managing security-related efforts is likely to hinge on its overall ability to manage its use of information technology.


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