Words similar to high-scoring

Example sentences for: high-scoring

How can you use “high-scoring” in a sentence? Here are some example sentences to help you improve your vocabulary:

Conservation alone is an insufficient criterion for assessing the validity of a miRNA [ 46 ] . Indeed, one high-scoring candidate (number 78, 2L:13233310 that is strongly conserved in Anopheles and was identified by miRseeker appears to be an unannotated U2 snRNA [ 43 ] . Nevertheless, our high success rate (20/27) leads us to believe that failure to observe expression of a high-scoring, third-species-conserved miRseeker candidate could reflect a false-negative result.
For example, BLAST provides alignment results composed of high-scoring pairs (HSPs) indicating local regions of similarity, but in total these typically do not provide the best global alignment over the entire length of the peptide to the genomic sequence.
With these concerns in mind, we tested 38 candidate genes from two classes of predicted miRNAs: 27 that were conserved outside of Drosophila (25 of which were high-scoring candidates) and 11 high-scoring, Drosophila -specific candidates.
We ultimately chose parameters that maximized the number of high-scoring pathways produced with real interactions, while minimizing high-scoring pathways from the randomized interactions.
Expression of 24 novel miRNA genes was verified by northern analysis (including 20 out of 27 candidates that were supported by third-species conservation and 4 out of 11 high-scoring predictions specific to Drosophila ), demonstrating that the bioinformatic screen was successful.