Example sentences for: high-resolution

How can you use “high-resolution” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • High-resolution mapping and chromosome walking, critical steps in the positional cloning of a mutant gene, may become problematic and tedious without high-density molecular markers.

  • High-resolution genetic maps are essential to identifying and characterizing the gene(s) contributing to diseases, that is, they are essential for making the transition from positional cloning to the positional candidate approach.

  • LOH and CGH analyses have consistently shown frequent loss of genomic material in a number of chromosomal regions suggesting the presence of potential tumor suppressor genes at these sites [ 4 6 15 16 ] . Of these, chromosome 5p deletions have been noted to be very frequent in invasive CC [ 5 6 7 ] . However, the locations of exact regions of LOH are not known because of a lack of systematic and high-resolution deletion mapping of the 5p region in CC.

  • Radiation hybrid mapping was used to localize the MADS on human chromosomes using high-resolution Gene-Bridge 4 radiation hybrid panels (Research Genetics, Inc, Carlsbad, CA, USA).

  • Minor rearrangements of microsyntenic genes could potentially impede high-resolution mapping if placement of the syntenic markers within a relatively large segment indicated a missing sequence fragment, as reported for the comparative mapping of maize and sorghum [ 31].


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