Example sentences for: high-fitness

How can you use “high-fitness” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • But as more random mutations are added, high-fitness genotypes become less common, and the average harm of multiple mutations is stronger than what the effect of single mutations indicated.

  • This correlation is fully consistent with the hypothesis that directional epistasis depends on the location of the reference sequence relative to other high-fitness genotypes.

  • By contrast, if a sequence is located at the periphery of a high-fitness cluster, or in a region of low density of high-fitness sequences, then this synergistic tendency is lessened, and we might even observe antagonistic epistasis for this sequence.

  • Consider a sequence that lies near the center of a dense cluster of high-fitness sequences.

  • The correlation between average mutational effects (α) and directional epistasis (β) described by Wilke and Adami [ 11 ] implies that whether a reference sequence shows synergistic or antagonistic epistasis depends on whether it lies near the center of a dense cluster of high-fitness sequences in genetic space, or on the fringes of such a cluster.


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