Words similar to high-affinity

Example sentences for: high-affinity

How can you use “high-affinity” in a sentence? Here are some example sentences to help you improve your vocabulary:

BMPs activate Smad-1 by binding to type I and type II serine-threonine kinase receptors [ 40 41 ] . Specific receptor subunits shown to bind BMPs include BMP receptor type IA (BMPR-IA), BMPR-IB, BMR-II, activin receptor type I (ActR-I), and ActR-II [ 42 43 44 ] . BMP ligands can bind to either type I or type II receptor subunits independently, but both receptor types are required for high-affinity binding and signaling [ 40 ] . The finding that the soluble BMPR-IA-Fc chimera significantly inhibits BMP-5 induced dendritic growth suggests that BMP-5 may be activating the Smad-1 signaling pathway via interactions with BMPR-IA.
The binding reactions were performed in a total volume of 10 μl in a buffer consisting of 10 mM Tris (pH 7.9), 50 mM KCl, 10% glycerol, 50 μg/ml BSA, 1 mM DTT, 10 mM Hepes, 5 mM MgCl 2 , 10 μg/ml calf thymus DNA, and 1.25 fmoles of double-stranded oligonucleotide bearing a high-affinity NFAT site (murine IL-4 promoter from -82 to -64).
Prolonged ethanol exposure decreases high-affinity choline uptake in rat cerebral cortex [ 21], and acute ethanol exposure decreases choline transport in erythrocytes [ 22].
Slc5a7 encodes a high-affinity choline transporter expressed in cholinergic neurons in the brain and spinal cord.
This pattern of mutations has been described for cold agglutinins [ 32], as well as for rheumatic factors, as a mechanism of selection against amino acid replacement to prevent the generation of high-affinity autoantibodies [ 33].