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Example sentences for: hhv-
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One patient had coinfection of EBV and HHV-6 during anticancer treatment detected by PCR [EBV (+++) positive, HHV-6 (+)] with serological evidence of primary EBV infection and reactivation of HHV-6.
Frequent infection with herpesviruses has long been recognized in patients undergoing allogeneic transplantation [ 7 8 ] and in patients with acute leukemia [ 1 2 ] . In patients with acute leukemia it has been reported that as many as two thirds of seropositive patients can develop reactivation of herpes simplex virus infection during remission induction therapy [ 26 ] . The risk of CMV infection in acute leukemia patients was recognized almost 30 years ago [ 27 ] but is of particular concern in patients undergoing allogeneic transplantation [ 2 28 ] . EBV infection is frequently associated with post-transplantation lymphoproliferative disorders in T cell-depleted grafts [ 29 ] . As recently reported, HHV-6 can also be associated with bone marrow supression [ 30 ] , encephalitis and pneumonitis [ 7 8 ] after allogeneic transplantation.
The age measure was also significantly different (p < 0.0001) demonstrating increasing HHV-6 IgG positivity with age.
ELISA testing kit (DIESSE ®, Germany) was used to test the EBV VCA IgM, EBV VCA IgG, EBV EBNA IgG antibodies [ 20 ] and ELISA testing kit (MEDAC ®, Czech Republic) was used to test the CMV IgM and CMV IgG antibodies in patient sera [ 21 ] . Immunofluorescence assay (IFA) kit (BAG ®, Germany) was used to test the HHV-6 IgM and HHV-6 IgG antibodies [ 22 ] . All tests were performed according to manufacturer's instructions.
EBV VCA IgG, CMV IgG and HHV-6 IgG seropositivity, respectively, was significantly different in the leukemia group (p = 0.0004; p < 0.0001; resp.
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