Example sentences for: hemizygous

How can you use “hemizygous” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Hoxd-4 transgenic mice were generated using the same transactivator strain crossed to the IE-d4-70 transresponder strain [ 1 ] . Maintenance and genotyping of transgenic mice was done as described before [ 1 23 ] . Unless otherwise noted, cells and samples were obtained from animals hemizygous for both transgenes.

  • Since MAOA is located on the X-chromosome, males are genetically hemizygous and females are functionally hemizygous due to random X-inactivation.

  • 5Cand 5D, previously summarized in [ 27 ] ). Both the reactivation of E82's GFP-COP1 transgene expression as well as suppression of endogene silencing were maintained for up to four additional generations in the absence of C73 in hemizygous and homozygous families, while C73 remained silenced (Fig.

  • Disease-causing myocilin mutants are less soluble in Triton [ 16 ] and are retained by the cell [ 12 ] . Other studies have shown that a truncated form of myocilin does not get secreted [ 20 21 ] and that mouse MYOC knockouts are without discernable phenotype [ 42 ] . Furthermore, a human hemizygous individual containing an interstitial deletion of chromosome 1, which encodes MYOC , was without evidence of glaucoma [ 43 ] and another patient homozygous for a severly truncated form of myocilin had no evidence of glaucoma [ 44 ] or other discernable phenotypes.

  • 5); and second, the GFP-COP1 expression of E82 gradually reverted back from the reactivated pattern to the silenced pattern especially in hemizygous families (Fig.


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