Example sentences for: helicase

How can you use “helicase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These data demonstrate that the helicase activity and C-terminal domain directed nucleolar localization of BLM is essential to maintain genomic stability.

  • The protein encoded by ORF2S (designated PEVE E1) is homologous to the helicase domain of superfamily 3 (SF3) viral helicases, such as E1 proteins of papillomaviruses (Figure 3) [ 18 19 20 ] . Similar to SF3 helicases, the PEVE E1 domain contains a P-loop (motif A) and two conserved motifs (B and C) that determine helicase function [ 18 19 ] . However, unlike SF3 helicases, PEVE E1 contains only the helicase domain with no additional protein domains.

  • Previous work from this laboratory and others [ 10, 17, 18, 19] demonstrated the DNA helicase activity of BLM in vitro on a variety of DNA substrates.

  • Cell lines with a favored reproductive potential grew well and multiple useful stable transfectants were obtained (normal BLM and N-terminal deletion genes) as compared to those containing deleterious mutant alleles (helicase and C-terminal deletions).

  • The GFP-BLM fusion protein has helicase activity in vitro and functions to reduce the SCE frequency in BS cells.


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