Words similar to helicase

Example sentences for: helicase

How can you use “helicase” in a sentence? Here are some example sentences to help you improve your vocabulary:

Transfection of the normal BLM cDNA (but not missense alleles lacking helicase activity) into BS cells reduces the frequency of SCEs [ 10], indicating that the DNA helicase activity of BLM is essential for genomic stability.
Compared to the normal BLM protein, deletions of the C-terminus and mutation of the helicase domain have a strong negative effect on genomic stability whereas deletions of the N-terminus have less effect.
These data demonstrate that mutation of the helicase and C-terminal domains of BLM have a greater effect on the SCE frequency than does mutation of the N-terminal domain.
As both the helicase activity and the C-terminus of BLM are required to maintain genomic stability it is likely that the C-terminus of BLM recognizes abnormal DNA structures and the helicase activity unwinds these multi-stranded structures to engender efficient repair.
The helicase and C-terminal mutations that fail to localize normally in the nucleolus fail to reduce the SCEs and implicate the nucleolus as a functional location for BLM during DNA replication.