Words similar to helicase

Example sentences for: helicase

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These data demonstrate that mutation of the helicase and C-terminal domains of BLM have a greater effect on the SCE frequency than does mutation of the N-terminal domain.
The protein encoded by ORF2S (designated PEVE E1) is homologous to the helicase domain of superfamily 3 (SF3) viral helicases, such as E1 proteins of papillomaviruses (Figure 3) [ 18 19 20 ] . Similar to SF3 helicases, the PEVE E1 domain contains a P-loop (motif A) and two conserved motifs (B and C) that determine helicase function [ 18 19 ] . However, unlike SF3 helicases, PEVE E1 contains only the helicase domain with no additional protein domains.
The GFP-fusion proteins with helicase mutations are packaged into the NBs and have altered nucleolar localization.
The highly acidic carboxy-terminal (BRCT) region of BRCA1 has been suggested to play a role in transactivation [ 11 ] . BRCT interacts with BRCA2, Rad51, other tumor suppressing elements, as well as numerous transcription factors, such as RNA helicase A and STAT1 [ 15 16 ] . Recently, it has been discovered that truncation of this region resulted in suppression of apoptosis following pro-apoptotic stimuli [ 17 ] . Further, these studies also suggested that the BRCT region facilitates apoptotic functions within the caspase pathway.
The helicase and C-terminal mutations have a destabilizing effect