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Example sentences for: harboring

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The generation of Hoxc-8 transgenic mice and the characterization of their phenotype have been published [ 1 ] . Briefly, Hoxc-8 expressing mice are generated in a binary transgenic mouse system [ 44 ] by crossing a transactivator strain (harboring a transgene in which expression of the transcriptional transactivator VP16 is under control of the Hoxc-8 promoter; [ 45 ] ) to a transresponder strain (that carries as a transgene the Hoxc-8 cDNA linked to the ICP4 immediate early gene promoter, which is silent in mice in the absence of VP16; [ 45 46 ] ). Upon combination of both transgenes, the Hoxc-8 transresponder transgene is activated, and Hoxc-8 becomes overexpressed [ 23 ] . This system also allows the generation of transgenic mice with increased gene dosage by superimposition of transgene loci to homozygosity [ 23 44 ] . For the studies reported here, we used the T239 transactivator and the IE-c8-254 transresponder strains.
I confess to harboring some soft sentiments for Brown, though my West Coast friends have always said he's easier to admire from 3,000 miles away.
U1 is a monocytic clone harboring two copies of the viral genome from parental U973 cells.
Such heterogeneity in the stage specificity of genetic events has also been shown for other chromosomal regions harboring tumor suppressor loci [ 11, 12, 13].
In addition, Genemap'99 for cDNA was integrated into the genomic clones harboring HINT consensus transcripts.