Example sentences for: half-life

How can you use “half-life” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The NF-κ B target gene A20 , an inhibitor of tumor necrosis factor (TNF)-induced apoptosis [ 28], is expressed in OCI-Ly3 cells and had a very short mRNA half-life.

  • This is manifestly an unusual dose schedule for a preparation with a circulating half-life of only about 12 min that is being targeted to a relatively small number of receptors.

  • The mRNA half-life for each drug treatment was computed as the negative of the inverse of the coefficient for each drug:

  • The half-life of myosin between these pools has been measured to be ~ 7 sec, indicating the importance of dynamic assembly control in the localization of the protein) [ 5 ] . When a cell migrates, myosin II accumulates in the posterior of the cell.

  • It has been shown that in Paget's disease of bone, a condition characterised by a localised upregulation of bone turnover, there is a significant increase in the ratio between the native peptide form of CTX (α L) and the age-modified forms (β L, D-isoaspartyl peptide and α D) [ 9 ] . The use of CTX ratios may thus be indicative of the significant decrease in the residence time and therefore the average age of the resorbed bone collagen type I fragments in Pagetic patients [ 9 ] . This indicates that perturbations in the normally well-regulated process of bone turnover can result in changes in the half-life of collagen type I within the bone matrix.


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