Words similar to hairpin
Example sentences for: hairpin
How can you use “hairpin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Methods for improving accuracy include simultaneous detection of two alleles per well, probes designed to contain hairpin sequences that regulate ligation discrimination and prevent nonspecific amplification, and introduction of a Q-PNA fluorescent detection system [ 9 ] . Improvements in probe design, rolling circle reaction design, and assay methods were integrated into an improved high accuracy genotyping assay, and the utility of the method was demonstrated for four clinically important mutations.
Expression of inverted-repeat constructs, where the transcript is expected to fold into a dsRNA hairpin, has been shown to be an efficient initiator of RNAi [ 13, 14, 15].
If the probe does not encounter the correct target, the hairpin will remain self-annealed, reducing the possibility of nonspecific or transient annealing events.
The HhH domain is a small nucleic acid-binding module comprised of two helices joined by a central loop (hairpin), which functions as the DNA-binding moiety of numerous repair and recombination proteins [ 27 28 ] . Two HhH modules are predicted in the core conserved domain of the RAD52 family, the first one bounded by the predicted helices 2 and 3, and the second one bounded by helices 5 and 6 (Fig.
P1 is an "Amplifluor™"-primer, with a 5' hairpin and loop structure with a fluorophore and quencher at the base of the hairpin arms [ 13 12 16 ] . The two allele-specific OCPs have different backbone sequences complementary either to a FAM- or TET- labeled P1 allowing discrimination of the polymorphic base.
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