Words similar to gβγ

Example sentences for: gβγ

How can you use “gβγ” in a sentence? Here are some example sentences to help you improve your vocabulary:

Signaling by the IGF-IR has been studied in many different cell types and is important for proliferation, survival, motility, adhesion, transformation, tumor formation and metastasis [for reviews see refs [ 31 32 ] ]. The receptor can directly phosphorylate the insulin receptor substrate 1 (IRS-1) and Shc proteins in the intact cell causing activation of PI-3Kinase and ras signaling [ 33 ] . More recently, it has been shown that the IGF-IR signals via the Gβγ subunits of the heterotrimeric Gi complex to stimulate PI-3Kinase and ras, and also activates the JAK/Stat pathway to cause phosphorylation of Stat3 [ 34 35 ] .
Earlier, we presented evidence that a regulator of G protein signaling, RGS3, might participate in the regulation of GnRH receptor signaling [ 9 ] . The mechanism of RGS action is antagonism of the Gα protein either by accelerating its hydrolysis of GTP, thereby prematurely terminating signaling due to reassociation of the Gα and Gβγ complexes [ 10 ] , or by antagonizing interaction of the Gα protein with its effector such as phospholipase Cβ [ 11 12 ] . A large number of RGS genes have been identified in mammals based on the presence of a 120 amino acid core domain [ 13 14 15 16 ] . RGS proteins have been described that interact with the G i α and G qα members of the G protein family [ 17 18 19 20 21 ] .
GPCRs stimulate heterotrimeric G proteins which release activated Gα and Gβγ subunits to interact with a variety of effectors.