Words similar to gα
Example sentences for: gα
How can you use “gα” in a sentence? Here are some example sentences to help you improve your vocabulary:
Taking the G protein-coupled receptors (GPCRs) as an example, after agonist action, GPCRs activate G proteins and become phosphorylated by G protein-coupled receptor kinases [ 23 ] . This event promotes activation of effector enzymes and ion channels by the activated Gα GTP.
In spite of its unknown functional significance, sα i2 provides a potential model for studying mechanisms of subcellular localization of Gα.
GPCRs stimulate heterotrimeric G proteins which release activated Gα and Gβγ subunits to interact with a variety of effectors.
Several studies have shown that deletions or amino acid substitutions in the extreme C-terminal region of Gα creates a protein defective in guanine-nucleotide binding [ 5 6 7 8 9 10 ] . Rapid release of guanine-nucleotides can result in an unstable Gα [ 9 10 ] . This leads to the prediction that sα i2 is also unstable due to a disruption in the structure of its C-terminus caused by the novel splice sequence.
Moreover, our finding that GnRH-stimulated IP 3 production was inhibited supports the locus of the RGS3 effect as residing at phospholipase C or earlier in the transduction pathway, most likely at the Gα protein because of our studies both earlier [ 9 ] and here showing that RGS3 binds Gqα in vitro.