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Example sentences for: gusto-iib

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Committee physicians reviewed events for almost 50% of the patients in the trial, which is nearly double the percentage that underwent adjudication by the same CEC group in two other trials: Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis (IMPACT-II) [ 9], and Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes (GUSTO-IIb) [ 1].
Finally, more cardiac enzyme samples were collected per patient in the PURSUIT trial than in GUSTO-IIb (median [25 th, 75 th] 4.5 [ 3, 7] versus 3 [ 1, 4]) (RAHarrington, unpublished data).
The reasons for disagreements in MI assessment between the site investigators and the CEC in the PURSUIT trial (Tables 1and 2) are similar to those seen in the Global Use of Strategies to Open Occluded Arteries in Acute Coronary Syndromes (GUSTO-IIb) and the Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis (IMPACT-II) trials (unpublished personal data).
For example, criteria for MI after bypass surgery in the GUSTO-IIb trial were more stringent than those in the PURSUIT trial, requiring two of three criteria to be met (CK or CK-MB fraction ≥ 5 times the upper limit of normal, two new Q waves, or new regional wall-motion abnormalities).