Words similar to groove

Example sentences for: groove

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Notes on Groove
CC-1065 (Figure 1) is among the most potent antitumor agents discovered [ 9 10 11 12 13 ] . It binds to double-stranded B-DNA within the minor groove with a sequence preference for 5'-d(A/GNTTA)-3' and 5'-d(AAAAA)-3', and alkylates the N3 position of the 3'-adenine with its left-hand CPI segment [ 14 15 ] . CC-1065 also inhibits gene transcription by interfering with binding of the TATA box-binding protein to its target DNA [ 16 ] . Despite its high potency and broad spectrum of antitumor activity, CC-1065 cannot be used in humans because it causes delayed death in experimental animals [ 17 ] . To pursue compounds possessing the potent antitumor activity but devoid of the toxic side effects of the parent compound, many CC-1065 analogues have been synthesized [ 18 19 20 21 22 23 24 25 26 ] .
Cartilage-bone cores of 5mm or 7mm in diameter were harvested from young bovine femoropatellar groove articular cartilage within 24 hours of slaughter.
The NarL interactions with the dmsA promoter region occurred at ten bp intervals and were offset by 3 bp in the 3' direction, suggesting the assembly of multiple NarL-phosphate molecules onto one face of the DNA that protect the minor groove.
There is a hint of a neural groove on its surface.