Example sentences for: grk

How can you use “grk” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The results of the current investigation as well as those presented earlier [ 31 ] nominate two molecular mechanisms as playing roles in setting the responsiveness level of GnRH receptor signaling; i.e., the RGS3 system acts at the G protein transducing step and the GRK/β arrestin system acts at the level of the receptor.

  • Because these are potential GRK phosphorylation sites, our data further suggest that GRK phosphorylation may be involved in down-regulation of the alpha-2C adrenergic receptor.

  • The opossum alpha-2C adrenergic receptor has a EESSTSE acidic serine/threonine motif in the third intracellular loop (Figures 1and 2), which could be a substrate for GRK based on the EESSSSD motif of the alpha-2A subtype.

  • One of these is Grk2 , a member of the family of ionotropic glutamate receptor genes that is thought to play a role in modulating Huntington disease [ 44].

  • Initial uncoupling of the beta-2 receptor from the G protein after agonist binding is mediated by phosphorylation by G protein-coupled receptor kinase (GRK) of specific residues in the carboxyl tail of the receptor.


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