Words similar to grb

Example sentences for: grb

How can you use “grb” in a sentence? Here are some example sentences to help you improve your vocabulary:

Thus Btk:ER appears to induce ERK activation through its capacity to activate PLCγ2, and not through a Grb2/Sos pathway.
Two different BCR signaling pathways can result in ERK activation in DT40 cells, namely a PLCγ2-independent Grb2/Sos pathway and a PLCγ2-dependent pathway that requires protein kinase C [ 38].
Indeed, the potential in vitro binding of the amino-terminus of Rlk to the SH3 domain of Grb2 hints of similar protein interactions.
Despite numerous reported differences, it does appear that diverse GPCRs share common mechanistic themes during ERK stimulation, including the tyrosine-phosphorylation of Shc and its complexing with Grb2, mSOS recruitment, the GTP-loading of Ras, and Raf-1 activation leading to MEK-1 phosphorylation [ 1 ] . However, the progression of each of these downstream events after GPCR stimulation depends first on the tyrosine phosphorylation of a membrane-bound protein that will be used as a scaffold, which will bind the other proteins (e.g.
Shc, Grb2, Gab1, mSOS.