Example sentences for: granisetron

How can you use “granisetron” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The W89F mutation produces a 18-fold change in K d for [ 3H]-granisetron binding (18 ± 2 nM) and the W89Y mutation produces a 5.8-fold change in K d (5.

  • Analog 1 is far less similar to lerisetron and more similar to the 5-HT 3 R antagonist granisetron.

  • The K i value for lerisetron inhibition of [ 3H]-granisetron binding to wildtype receptors was determined to be 0.8 ± 0.19 nM (Figure 3and Table 1).

  • Previous studies concluded that R91 was an important interaction for the 5-HT 3 R agonist 5-hydroxytryptamine (5-HT), since the K i for 5-HT inhibition increased over 3000 fold as a result of the R91A mutation [ 24 ] . A change in K d for [ 3H]granisetron binding to R91A was also observed.

  • Figure 4Dshows the inhibition of [ 3H]-granisetron binding by analogs 1 and 2 at R91A mutant receptors.


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