Words similar to granisetron
Example sentences for: granisetron
How can you use “granisetron” in a sentence? Here are some example sentences to help you improve your vocabulary:
The K i values for inhibition of [ 3H]granisetron binding by all four compounds are shown in Table 3. Little change in K i value was observed for the majority of mutations.
[ 3H]granisetron does not appear to interact with any of the amino acids tested while d -tc interacts with only Y140, m CPBG and 5-HT with Y142 and lerisetron with both Y142 and Y152.
This result indicates the lack of involvement of amino acids in this binding loop in the binding of [ 3H]granisetron.
In addition, the increase in K i was identical to the increase in K d that has been observed for [ 3H]granisetron binding on this mutant [ 24 ] . Alterations in K i resulting from the W89Y mutation were slightly less, however the change was again the same for lerisetron, analog 1 and analog 2. These data suggest that all three compounds form binding site interactions with W89.
Figure 3shows inhibition of [ 3H]-granisetron binding by lerisetron on wildtype and mutant receptors.
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