Example sentences for: granisetron

How can you use “granisetron” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Only two mutant receptors failed to bind [ 3H]granisetron; G147A and V149A.

  • The K i value for lerisetron inhibition of [ 3H]-granisetron binding to wildtype receptors was determined to be 0.8 ± 0.19 nM (Figure 3and Table 1).

  • These data agree well with previously reported values [ 24 ] . Alanine mutations at the tyrosine positions Y140, Y142 and Y152 also produced minor increases in K d for [ 3H]granisetron binding (2.

  • The K i values for inhibition of [ 3H]granisetron binding by analogs 1 and 2 were altered only slightly by the Y142A mutation.

  • These data suggest that, while the receptors do assemble and are capable of binding [ 3H]granisetron, they are either not transported to the cell surface or are non-responsive to 5-HT at concentrations of 1 mM or less.


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