Words similar to gold-domain
Example sentences for: gold-domain
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Thus, the GOLD-domain proteins of category 2 may have a specific role in regulating the secretion of molecules that are not affected by the p24 proteins.
With the exception of the p24 proteins, which have a simple architecture with the GOLD domain as their only globular domain, all other GOLD-domain proteins contain additional conserved globular domains (Figure 2).
The domain architecture and evolutionary history of GOLD-domain proteins: functional implications
The presence of extensive coiled-coil segments in some of the category-2 GOLD-domain proteins, such as FYCO1, suggests that they might also form oligomers, like the p24 proteins.
Thus, all GOLD-domain proteins can be divided into two architectural categories: the p24-like category, in which the GOLD domains project into the lumen, anchored in the membrane by the membrane-spanning helix (category 1); and proteins in which the GOLD domain occurs at the extreme amino or carboxyl terminus, with additional domains that are known to interact with lipid membranes (category 2) (Figure 2).