Words similar to glp
Example sentences for: glp
How can you use “glp” in a sentence? Here are some example sentences to help you improve your vocabulary:
For NAHR to have had a role, however, one must presume the presence of a GLP/LCR15-related sequence on the ancestral 15p.
[ 21 ] . The roughly 30 kb GLP/LCR15 duplicon is present in approximately eight copies throughout the 600 kb duplication-rich sub-interval (Figure 4).
Interestingly, the extent of the segmental duplications in the 1 Mb region examined was restricted to the clones that showed the dual FISH signal in PTR XVp and XVq and each clone that produced dual FISH signals contained a GLP/LCR15 duplicon by sequence analysis (Figure 4).
With our results indicating the CHRNA7 sequence is single copy in the chimpanzee genome and thus unlikely to be involved in the inversion, the GLP/LCR15 duplicon is therefore the best candidate sequence for being present at the site of the pericentric inversion.
On the basis of the findings of Pujana et al ., the GLP/LCR15 duplicon is present at multiple regions of human genomic instability [ 21 ] . In addition, the GLP/LCR15 duplicon was shown by Gilles et al . to be polymorphic in the human population - showing that these sequences have considerable intraspecific plasticity [ 18 ] . The GLP/LCR15 duplication family has expanded over the last 20 million years of primate evolution, before the divergence of the great ape lineages, resulting in a multitude of copies (estimated at 27) present at multiple sites along chromosome 15, providing the conditions required for rearrangements driven by nonallelic homologous recombination (NAHR) [ 18 19 21 27 ] . We have begun an investigation of the organization of this region within the chimpanzee lineage.
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