Words similar to glp
Example sentences for: glp
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[ 21 ] . The roughly 30 kb GLP/LCR15 duplicon is present in approximately eight copies throughout the 600 kb duplication-rich sub-interval (Figure 4).
3 previously described by Riley et al . [ 17 ] , and several copies of a duplicon described as Golgin-linked-to-PML (GLP) [ 18 ] and as LCR15 [ 19 20 21 ] . A third, previously undetected, potential segmental duplication was identified in the proximal third of the 600 kb region (Figure 4, indicated by the asterisk).
Interestingly, the extent of the segmental duplications in the 1 Mb region examined was restricted to the clones that showed the dual FISH signal in PTR XVp and XVq and each clone that produced dual FISH signals contained a GLP/LCR15 duplicon by sequence analysis (Figure 4).
With our results indicating the CHRNA7 sequence is single copy in the chimpanzee genome and thus unlikely to be involved in the inversion, the GLP/LCR15 duplicon is therefore the best candidate sequence for being present at the site of the pericentric inversion.
For NAHR to have had a role, however, one must presume the presence of a GLP/LCR15-related sequence on the ancestral 15p.