Words similar to globin

Example sentences for: globin

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Despite this common genetic background, phenotypic expression of sickle cell disease is widely variable, ranging from a mild, asymptomatic course with survival into the sixth or seventh decade to a very severe course with multi-organ damage and early mortality [ 1 ] . Some of the genetic factors contributing to this phenotypic diversity (particularly those linked to the globin genes, i.e. α-thalassemia and β-globin gene cluster haplotypes) have been well recognized [ 2 ] .
The results for the globin family are given in Figure 4. On average, using the all-atom function improves model quality by 0.8 Å C α RMSD compared to only using sequence identity.
However, neither direct comparisons, nor sequence-structure threading revealed any relationship with the two other well-characterized α-helical heme-binding domains, namely globin and cytochrome C. Hence, it is likely that the HNOB domain adopts a structure distinct from these domains.
We thus devised an experiment where we constructed models for protein families with large numbers of known structures (specifically the globin and the immunoglobulin families).
We then conducted an all-against-all homology modelling exercise where every member of the family was modelled on every other template (resulting in 29 and 60 models for each member of the globin and immunoglobulin families respectively).