Words similar to gln
Example sentences for: gln
How can you use “gln” in a sentence? Here are some example sentences to help you improve your vocabulary:
Lhcb6, a minor LHCP, contains Gly instead of Pro at the position analogous to 82 in Lhcb1, thus eliminating the peptide bond carbonyl of Gly as a ligand, but Lhcb6 has a potential ligand for Chl b in Gln83 [ 39 40 ] . These two LHCP sub-species, along with Lhca4 are most affected by the lack of Chl b in vivo [ 5 ] . Lhcb4 (apoprotein of CP29) has Val instead of Pro at 'position 82', and the absence of site a 6 in Lhcb4 may contribute to its drastic reduction in Chl b -less mutants [ 5 8 ] . However, Lhcb2, Lhcb3, Lhca1, Lhca2 and Lhca3 contain the Gly peptide carbonyl as a ligand (each has Pro at 'position 82' [ 40 ] ) but are reduced only slightly, if any, in amount by the lack of Chl b.
An alternative mechanism for the formation of inclusion bodies in protein conformation disorders is suggested by a recent study showing that clearance of poly-Gln and poly-Ala inclusions is accelerated by compounds like rapamycin, which stimulate protein degradation by autophagy [ 64 ] . Along similar lines, the work of Kegel et al . [ 65 ] hints that poly-Gln huntingtin may be degraded mainly in autophagic vacuoles containing lysosomal proteases.
Specifically, they found that when aggregates from 293 cells expressing poly-Gln proteins were dissociated, the ubiquitin polymers were not conjugated directly to the poly-Gln protein or the sequestered Hsp70.
Four residues in the vicinity of the ligands are varying from one receptor isotype to the other: Thr183 of alpha4 (Ser in alpha3 and alpha7), Ala135 of beta2 (Leu in beta4 and Val in alpha7), Phe144 of beta2 (Leu in beta4 and Gln in alpha7), and Thr83 of beta2 (Lys in beta4 and Gln in alpha7) (Figure 1).
This change resulted in loss of one Chl b after reconstitution [ 34 ] . Gln 131 ( b 6) and Glu 139 (in an ion-pair with Arg142) ( b 5) were also identified as ligands to Chl b [ 31 34 35 36 ] . Remelli et al.
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