Words similar to gln
Example sentences for: gln
How can you use “gln” in a sentence? Here are some example sentences to help you improve your vocabulary:
Although this model implies that the misfolded poly-Gln protein might be the primary substrate for ubiquitination, a recent study by Suhr et al . [ 60 ] suggests that this may not always be the case.
However, there are many case reports describing patients with progressive neurodegenerative disorders of unknown etiology, collectively referred to as neuronal intranuclear inclusion disease [ 77 ] . While these may consist mainly of unidentified poly-Gln or poly-Ala disorders, the present study raises the possibility that some forms of this disease may arise through unexpected mechanisms, perhaps involving mutations in Rab24 or other poorly characterized members of the Rab GTPase family that mediate trafficking of misfolded proteins within autophagosomes and lysosomes.
This change resulted in loss of one Chl b after reconstitution [ 34 ] . Gln 131 ( b 6) and Glu 139 (in an ion-pair with Arg142) ( b 5) were also identified as ligands to Chl b [ 31 34 35 36 ] . Remelli et al.
Consistent with this prediction, a position in CP29, a minor LHCII, was preferentially filled during reconstitution by Chl a when the amino acid residue was the normal Glu, in an ion-pair with a bound Ca ++ion, but occupancy was shifted toward Chl b when the ligand was a weaker base, the amide group of Gln [ 31 ] . Although the on-rate for Chl b may be slower than that for Chl a, because binding may be impeded by a water molecule more strongly coordinated to the central Mg atom of Chl b, the greater Lewis acid strength of Chl b allows more stable bonds with the weaker ligands.
Specifically, they found that when aggregates from 293 cells expressing poly-Gln proteins were dissociated, the ubiquitin polymers were not conjugated directly to the poly-Gln protein or the sequestered Hsp70.
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