Words similar to gln
Example sentences for: gln
How can you use “gln” in a sentence? Here are some example sentences to help you improve your vocabulary:
To examine a wider range of promoter and polymerase combinations, a promoter library was constructed in which positions -8 through -11 in the promoter were completely randomized; each of these nucleotides had previously been shown to be extremely important for the specificity of interactions with T7 RNA polymerase [ 6 7 9 11 ] . Conversely, residues Asn 748, Arg 756, and Gln 758 were known to form sequence specific contacts with this region of the promoter [ 2 ] . The promoter library was combined with the gene library in order to create approximately 51,200 (4 4× 20 3) combinations of promoters and polymerases.
It will be interesting to determine whether Asw homodimers display any binding to Hint substrates, what degree of Hint enzyme activity is retained by the putative Hint-Asw heterodimer, and whether Gln127 is required for depression of Hint enzymatic activity in Hint-Asw heterodimers.
Values for f2 (the percentage of identical codons for conserved twofold-redundant amino acids - Cys, Asp, Glu, Phe, His, Lys, Asn, Gln, and Tyr) between two aligned proteins are calculated by looking at the codons' third position in positions at which amino acids with twofold degeneracy occur.
An alternative mechanism for the formation of inclusion bodies in protein conformation disorders is suggested by a recent study showing that clearance of poly-Gln and poly-Ala inclusions is accelerated by compounds like rapamycin, which stimulate protein degradation by autophagy [ 64 ] . Along similar lines, the work of Kegel et al . [ 65 ] hints that poly-Gln huntingtin may be degraded mainly in autophagic vacuoles containing lysosomal proteases.
As shown in Figure 3, Gln127 of Asw is predicted to alter the conformation of Hint His114 such that His114 is not positioned for productive hydrogen bonding, dominantly depressing hydrolase activity from the Hint active site.
Loading...