Example sentences for: glioma

How can you use “glioma” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • [ 1 ] identified developmentally regulated nuclear antigens recognized by SMI-31 mAB in C6 rat glioma cells in vitro as well as glial and neuronal nuclei in vivo , suggesting the presence non-neurofilament epitopes.

  • C6 glioma cells have been used as host cells for the transfection of several GPCR types, and have the advantage of expressing high levels of ERK, while being devoid of the EGFR.

  • SMI-31 mAB labeled F98 rat glioma nuclei and cytoplasm with equal or greater avidity than in SH-SY5Y cells (Figure 1D).

  • PTEN is altered or deleted in many human cancers [ 7 8 9 10 ] . In-vitro, cells that are deficient in PTEN show elevated PI-3Kinase signaling [ 11 ] . Reintroduction of PTEN in a variety of cancer cells, including glioma, breast, bladder and ovarian cancer cells, causes G1 arrest, inhibits tumorigenesis, and promotes anoikis [ 12 13 14 ] . Mechanistically, Akt activity is decreased, cell motility is decreased, expression of two cyclin-dependent kinase inhibitors p27 and p21 is increased, cyclin D1 is down-regulated, Rb phosphorylation is inhibited, and signaling via Grb2/SOS is suppressed [ 11 15 ] . The link between PTEN and cell growth is underscored by genetic experiments in mice.

  • One cell line is D-17, which is highly permissive to adenoviral infection when viral vectors are used free in solution [ 10 ] . The other cell line is C6 (rat glioma cells), which is less permissive to adenoviral infection [ 10 ] . For D-17 cells, the amount of infection increased steeply when the number of viral particles added to each well increased from 2.5 × 10 5to 2.5 × 10 6(Fig.


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