Example sentences for: gli

How can you use “gli” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The captain tooted his horn and called out over a megaphone, "Vivano gli sposi!

  • In particular, little is known about the means by which Ptc exerts its inhibitory effect on Smo, or how Smo communicates with the cytoplasmic Ci/Gli transcription factor complex.

  • Additional pathway components are thought to modulate the activity or subcellular distribution of these molecules [ 2 ] . There is positive and negative feedback at the transcriptional level as the Gli1 and Ptc1 genes are direct transcriptional targets of activation of the pathway.

  • We then introduced into each line a plasmid containing a luciferase reporter downstream of multimerized Gli binding sites and a minimal promoter [ 20 ] . An isolated stable clone of the 10T1/2 cell transfectants (referred to as clone S12) gave a 10-20-fold up-regulation of luciferase activity (Figure 1a) when stimulated with Hh protein [ 21 ] for 24 hours.

  • Using quantitative PCR, Hh-Ag 1.1 was shown clearly to elevate the expression of Gli1 and Ptc1 in a dose-dependent manner (Figure 1c).


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