Words similar to gli

Example sentences for: gli

How can you use “gli” in a sentence? Here are some example sentences to help you improve your vocabulary:

These include: a Hh-protein-blocking antibody, 5E1 [ 23 ] ; a natural product derivative, cyclopamine [ 9 10 ] that has recently been shown to act downstream of Ptc, perhaps at the level of Smo [ 11 ] ; a recently identified synthetic small-molecule inhibitor, Cur61414, which has inhibitory properties similar to cyclopamine [ 17 ] ; and forskolin, an adenylate cyclase/protein kinase A activator that is thought to block Hh signaling by stimulating degradation of members of the Gli family of transcriptional activators [ 2 ] .
Although no compelling data have been presented that directly link classic G-protein activation [ 37 ] to the canonical Hh pathway involving Ci/Gli stimulation [ 2 ] , recent studies show that under certain conditions Smo can engage G-protein subunits in a Ptc-dependent manner [ 38 ] and that G-protein-mediated cAMP modulation may underlie certain effects of Hh on neuronal tissue [ 39 ] .
After testing several cell lines for Hh-dependent induction of the target genes Ptc1 and Gli1 [ 2 ] , we identified C3H10T1/2 and TM3 cells as optimal responders.
The captain tooted his horn and called out over a megaphone, "Vivano gli sposi!
Using quantitative PCR, Hh-Ag 1.1 was shown clearly to elevate the expression of Gli1 and Ptc1 in a dose-dependent manner (Figure 1c).