Words similar to gleevec

Example sentences for: gleevec

How can you use “gleevec” in a sentence? Here are some example sentences to help you improve your vocabulary:

The assay is based upon the cleavage of the yellow tetrazolium salt MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] to purple formazan crystals by metabolically active cells [ 15 ] . The tested concentration of Gleevec ranged from 0.5 to 8 μM.
Gleevec has been shown to induce clinical, hematological and molecular remissions for CML patients [ 4 ] . It cross-reacts with two other important growth factor receptors containing tyrosine kinase domains, c-kit and PDGF receptors, that play important roles in growth and proliferation of a variety of cell types [ 5 ] . C-kit (also known as CD117) is frequently mutated in gastrointestinal stromal tumor (GIST), and the mutated c-kit shows higher tyrosine kinase activity.
These results provided important in vitro data to support the notion that Gleevec can inhibit the A549 cell growth and proliferation, and may potentially offer a treatment option for lung cancer either alone or in conjunction with chemotherapy drug cisplatin.
These results showed that Gleevec alone can indeed inhibit the growth of A549 lung carcinoma cells.
One of the major reasons of testing Gleevec for treatment of non-small cell lung carcinoma is to see if the specific tyrosine kinase inhibitor Gleevec, and other potential small molecules currently on clinical trials, can be used as an adjuvant therapeutic agent in combination with conventional chemotherapy.