Words similar to gleevec
Example sentences for: gleevec
How can you use “gleevec” in a sentence? Here are some example sentences to help you improve your vocabulary:
We have chosen to perform the experiments under the normal culture condition since we reasoned that the effect of Gleevec on tumor cells, if any, should be under the normal, not serum free condition.
A549 lung cancer cells were plated at two cell densities into the 96 well plates, and Gleevec was added to the culture medium.
One of the major reasons of testing Gleevec for treatment of non-small cell lung carcinoma is to see if the specific tyrosine kinase inhibitor Gleevec, and other potential small molecules currently on clinical trials, can be used as an adjuvant therapeutic agent in combination with conventional chemotherapy.
At the concentration of 4 μM or higher, the inhibitory effect of Gleevec on both A549 and 293 cells were found to be identical (Figure 2and 3).
Cisplatin causes two types of DNA damage, DNA adducts and inter-stranded cross-linking, resulting in activation of apoptosis pathway in the target tumor cells [ 13 14 ] . Our results suggest that inhibition of tyrosine kinase activity of the potential targets by Gleevec appear to potentiate the effect of cisplatin in DNA-damage induced apoptosis in A549 cells.