Example sentences for: glaucoma

How can you use “glaucoma” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In fact, all 31 amino acids (34 missense/nonsense mutations total) for human myocilin documented in the Human Gene Mutation Database http://uwcmml1s.uwcm.ac.uk/uwcm/mg/search/5584221.htmlto cause glaucoma are conserved in rabbit myocilin (Fig 2).

  • This suggests that MYOC haploinsufficiency is not causative for glaucoma and that myocilin may even be dispensable or redundant in normal human development or only important when ocular stress occurs.

  • Due to conservation in mammalian physiology and the powerful tools of mouse genetics, mice are a very important experimental system for probing the functions (both in health and disease) of many genes recently identified by sequencing the human genome [ 12 ] . We have focused on developing the mouse system for IOP and glaucoma studies [ 13 14 15 16 17 18 19 ] . Mice are expected to be extremely helpful in characterizing genes and mechanisms that affect IOP or the susceptibility of the optic nerve and retina to glaucomatous damage [ 20 ] .

  • Glaucoma is a leading cause of blindness but its molecular etiology is poorly understood.

  • These results add to our understanding of the natural history of glaucoma in mice and provide a new animal model for studying glaucoma involving increased IOP.


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