Example sentences for: germline

How can you use “germline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To test the "germline potential" of F3 cells we first generated chimeric mice by aggregating F3 ES cells with CD-1 morulae and allowing them to develop to term in utero.

  • There is a biased use of particular germline VH genes in the VH repertoire.

  • This has led to the development of tagged sequence mutagenesis, a process by which genes disrupted in ES cells are characterized at the nucleotide level prior to germline transmission [ 20 21 22 23 24 ] .

  • Turcot's syndrome is caused by germline mutations in the gene APC , a member of the Wnt signaling pathway.

  • These lesions tend to occur very rarely in the general population, but may occur with a high probability (sometimes 100%) in patients carrying the germline mutation.


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