Example sentences for: germline

How can you use “germline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The VH germline repertoire consists of 123 (44 functional) VH segments subdivided into seven VH families (see supplementary material).

  • This is important because each round of clonal selection increases the likelihood of losing germline competency of the ES cells.

  • Germline mutations that cause breast and ovarian cancer predisposition frequently result in truncated and presumably inactive BRCA1 protein [ 12].

  • Sequence-based screens are faster and less expensive than phenotype-based screens, and provide centralised collections of characterised mutations available for germline transmission.

  • AS = ankylosing spondylitis; CDR = complementarity determining region; DH = heavy chain diversity segment; FR = framework region; GC = germinal centers; gl = germline; JH = heavy chain joining segment; PCR = polymerase chain reaction; RA = rheumatoid arthritis; ReA = reactive arthritis; SM = synovial membrane; VH = heavy chain variable segment.


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