Example sentences for: germline

How can you use “germline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Germline mutations in the breast and ovarian cancer susceptibility gene BRCA1 , which is located on chromosome 17q21, are associated with a predisposition to the development of cancer in these organs [ 1, 2].

  • A novel germline variation, 568-573 insCCCCC, was present in both mother and the proband.

  • Five productively rearranged genes were highly mutated with a range of 12 (F5-3a3) to 29 mutations to their respective germline (gl) gene.

  • Turcot's syndrome is caused by germline mutations in the gene APC , a member of the Wnt signaling pathway.

  • JD introduced the 1B4 mutation into the germline, MR analyzed the 1B4 mutation in mice and cells and characterized the hnRNPB1/A2 cDNA and ER supervised the project.


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