Example sentences for: genomewide

How can you use “genomewide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The 28 polymorphisms in 20 candidate genes and the SNP markers in the genomewide screen will be genotyped by high-throughput SNP screening using the MassARRAY™ System (Sequenom Inc., San Diego, CA).

  • Defining the molecular basis for the inherited component to ischemic stroke risk will require converging lines of evidence from various methodologies, including genomewide screens [ 24 ] and candidate gene association studies.

  • Exploration of alternative selection criteria for cases and controls in our genomewide association study will be dependent on the combined TCD distribution of the 1000 to1400 new patients that will be screened as part of the STOP-II study and the 130 patients (TCD ≥ 200 cm/s) from the original STOP study that are already available.

  • The reason is simply that this approach has only recently become possible with the advent of high throughput SNP genotyping and we are not currently aware of any published studies that have used genomewide association for identification of susceptibility loci of complex traits.

  • In the meantime, replication of significant associations detected in the candidate gene part of the study with our genomewide approach should provide us with practical estimates for the likely density of SNP markers needed for successful LD mapping.


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