Example sentences for: generalized

How can you use “generalized” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, mutations in these genes do not cause generalized neurodegeneration; in fact, they tend to be more restricted and less progressive than, for example, α-synuclein mutations.

  • During the third trimester, and after 34-36 weeks of pregnancy in particular, the placenta may develop an abnormality, often classified as placental aging [ 19 20 21 22 23 24 ] . These abnormal placentae are characterized by generalized interstitial fibrosis and fibrinoid degeneration of villous stroma, and are associated with cellular apoptosis and congestion of villous sinusoids [ 24 25 26 27 ] . Immunohistochemically, villous abnormality is associated with progressive diminution of Thy-1 differentiation protein in the villous core [ 28 ] . Marked changes in villous structure are particularly associated with advanced maternal age [ 29 30 ] . We have recently reported that, with respect to the Thy-1 expression, compensatory dilatation of villous sinusoids, and placental expression of low molecular weight cyclin E variants, the term placentae can be classified into four placental types (PT1-PT4) [ 30 ] , where PT4 corresponds to the most severe placental abnormality.

  • Part of the chemopreventive efficacy of antiestrogens and retinoids in this model may therefore be due to a generalized decrease in ductal development.

  • That work [ 12 ] is hereby extended and further generalized to be applicable to sequences with arbitrary numbers of unique component units, without sacrificing the inverse correlation between distance in the map and sequence similarity independent of position.

  • Once the stain value at each pixel was determined, a generalized grouping was used to account for regional features, such as nuclei, which bind the stain.


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