Example sentences for: gelatinases

How can you use “gelatinases” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is hypothesized that an imbalance between the activators and inhibitors of the gelatinases results in higher levels of activity, enhanced local proteolysis, and bone erosion.

  • Although the evidence is indirect, these data are consistent with the hypothesis that high levels of activated synovial gelatinases reflect augmented synovial invasiveness; these observations are similar to those made in the context of invasive cancers [ 16].

  • In patients with inflammatory arthritis the gelatinases are expressed in the synovial membrane, and have been implicated in synovial tissue invasion into adjacent cartilage and bone.

  • Few studies have evaluated the levels of active MMPs in situ . Gel zymography has proved to be a sensitive and effective method of detecting the activity of gelatinases in small tissue samples [ 20].

  • Overall, the present observations suggest an association between the presence of active synovial gelatinases and the early development of erosive articular damage.


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